Description
presenilin 2 (Alzheimer disease 4)
Synonyms
AD3L, STM2, PS2
Location
Chromosome 1: 226,870,184-226,896,102 forward strand.
VEGA68:CM000663.2
About this gene
This gene has 11 transcripts (splice variants), 2 orthologues and 1 paralogue.
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID | Biotype | CCDS | UniProt | Flags |
|---|---|---|---|---|---|---|---|---|
| PSEN2-001 | OTTHUMT00000091539.2 | 2306 | 448aa | OTTHUMP00000035671 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS1556 | P49810 | |
| PSEN2-007 | OTTHUMT00000091545.2 | 1947 | 447aa | OTTHUMP00000228286 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS44324 | - | |
| PSEN2-002 | OTTHUMT00000091540.2 | 2465 | 481aa | OTTHUMP00000035672 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | B1AP22 | |
| PSEN2-006 | OTTHUMT00000091544.2 | 1163 | 304aa | OTTHUMP00000228289 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E5RG63 | |
| PSEN2-005 | OTTHUMT00000091543.3 | 782 | 144aa | OTTHUMP00000228287 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E5RFW4 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| PSEN2-010 | OTTHUMT00000381592.3 | 734 | 21aa | OTTHUMP00000228284 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| PSEN2-004 | OTTHUMT00000091542.3 | 627 | 129aa | OTTHUMP00000228285 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E5RHT1 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| PSEN2-003 | OTTHUMT00000091541.3 | 1668 | No protein | - | <p>Error in the sequence in a public database (for example UniProtKB, NCBI RefSeq). Annotation is by the <a rel="external" href="http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html">VEGA/Havana</a> project.</p>Artifact | - | - | |
| PSEN2-009 | OTTHUMT00000091547.2 | 570 | No protein | - | <p>Transcripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.</p>Processed transcript | - | - | |
| PSEN2-008 | OTTHUMT00000091546.1 | 566 | No protein | - | <p>Transcripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.</p>Processed transcript | - | - | |
| PSEN2-011 | OTTHUMT00000381593.1 | 730 | No protein | - | <p>Alternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.</p>Retained intron | - | - |
