Description
topoisomerase (DNA) I, mitochondrial
Location
Chromosome 8: 143,304,384-143,359,979 reverse strand.
VEGA68:CM000670.2
About this gene
This gene has 21 transcripts (splice variants), 3 orthologues and 1 paralogue.
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID | Biotype | CCDS | UniProt | Flags |
|---|---|---|---|---|---|---|---|---|
| TOP1MT-005 | OTTHUMT00000381295.1 | 1982 | 503aa | OTTHUMP00000228104 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS59115 | - | |
| TOP1MT-003 | OTTHUMT00000381294.2 | 1960 | 503aa | OTTHUMP00000228103 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS59115 | - | |
| TOP1MT-001 | OTTHUMT00000381247.3 | 1958 | 601aa | OTTHUMP00000228063 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS6400 | Q969P6 | |
| TOP1MT-002 | OTTHUMT00000381248.2 | 1868 | 503aa | OTTHUMP00000228064 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS59115 | - | |
| TOP1MT-006 | OTTHUMT00000381299.3 | 1561 | 376aa | OTTHUMP00000228106 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E5RIC7 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| TOP1MT-016 | OTTHUMT00000381324.2 | 1007 | 201aa | OTTHUMP00000228121 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E5RJ95 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| TOP1MT-017 | OTTHUMT00000381323.2 | 906 | 221aa | OTTHUMP00000228120 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E5RFS0 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| TOP1MT-013 | OTTHUMT00000381321.1 | 892 | 111aa | OTTHUMP00000228119 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | H0YAR3 | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete |
| TOP1MT-020 | OTTHUMT00000381331.2 | 613 | 164aa | OTTHUMP00000228126 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E5RGR4 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| TOP1MT-011 | OTTHUMT00000381327.2 | 564 | 33aa | OTTHUMP00000228124 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E5RJ33 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| TOP1MT-021 | OTTHUMT00000381332.3 | 509 | 134aa | OTTHUMP00000228127 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E5RGE7 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| TOP1MT-015 | OTTHUMT00000381328.2 | 499 | 164aa | OTTHUMP00000228125 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E5RFE3 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| TOP1MT-009 | OTTHUMT00000381297.1 | 1896 | No protein | - | <p>Error in the sequence in a public database (for example UniProtKB, NCBI RefSeq). Annotation is by the <a rel="external" href="http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html">VEGA/Havana</a> project.</p>Artifact | - | - | |
| TOP1MT-008 | OTTHUMT00000381296.1 | 1882 | No protein | - | <p>Error in the sequence in a public database (for example UniProtKB, NCBI RefSeq). Annotation is by the <a rel="external" href="http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html">VEGA/Havana</a> project.</p>Artifact | - | - | |
| TOP1MT-007 | OTTHUMT00000381298.2 | 1461 | 167aa | OTTHUMP00000228105 | Transcript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins. Nonsense mediated decay | - | E5RGR2 | |
| TOP1MT-018 | OTTHUMT00000381325.1 | 874 | 49aa | OTTHUMP00000228122 | Transcript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins. Nonsense mediated decay | - | H0YBR3 | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete |
| TOP1MT-019 | OTTHUMT00000381326.1 | 698 | 123aa | OTTHUMP00000228123 | Transcript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins. Nonsense mediated decay | - | H0YC03 | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete |
| TOP1MT-004 | OTTHUMT00000381300.1 | 2029 | No protein | - | <p>Transcripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.</p>Processed transcript | - | - | |
| TOP1MT-010 | OTTHUMT00000381330.1 | 520 | No protein | - | <p>Transcripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.</p>Processed transcript | - | - | |
| TOP1MT-014 | OTTHUMT00000381329.1 | 313 | No protein | - | <p>Transcripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.</p>Processed transcript | - | - | |
| TOP1MT-012 | OTTHUMT00000381322.1 | 624 | No protein | - | <p>Alternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.</p>Retained intron | - | - |
