Description
caspase 8, apoptosis-related cysteine peptidase
Synonyms
FLICE, Casp-8, MCH5, MACH
Location
Chromosome 2: 201,233,443-201,287,711 forward strand.
VEGA68:CM000664.2
About this gene
This gene has 21 transcripts (splice variants), 6 orthologues and 4 paralogues.
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID | Biotype | CCDS | UniProt | Flags |
|---|---|---|---|---|---|---|---|---|
| CASP8-002 | OTTHUMT00000256278.3 | 2930 | 538aa | OTTHUMP00000163717 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS42798 | - | |
| CASP8-012 | OTTHUMT00000257912.2 | 2650 | 464aa | OTTHUMP00000165064 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS2343 | A0A024R3Z8 | |
| CASP8-006 | OTTHUMT00000257907.2 | 1906 | 496aa | OTTHUMP00000165062 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS42799 | - | |
| CASP8-009 | OTTHUMT00000257909.4 | 1630 | 464aa | OTTHUMP00000165063 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS2343 | A0A024R3Z8 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| CASP8-014 | OTTHUMT00000336853.2 | 1629 | 479aa | OTTHUMP00000206552 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS2342 | Q14790 | |
| CASP8-004 | OTTHUMT00000256281.1 | 1060 | 235aa | OTTHUMP00000163720 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS2345 | - | |
| CASP8-017 | OTTHUMT00000336856.2 | 1275 | 258aa | OTTHUMP00000206554 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | H7C0E2 | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete |
| CASP8-026 | OTTHUMT00000338655.2 | 717 | 116aa | OTTHUMP00000207361 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E7EQ01 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| CASP8-010 | OTTHUMT00000257910.3 | 707 | 209aa | OTTHUMP00000206581 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E7EQ06 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| CASP8-020 | OTTHUMT00000336859.11 | 686 | 149aa | OTTHUMP00000206555 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | C9JB29 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| CASP8-023 | OTTHUMT00000336861.11 | 658 | 198aa | OTTHUMP00000206557 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E7ETB7 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| CASP8-021 | OTTHUMT00000336860.2 | 592 | 124aa | OTTHUMP00000206556 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E7EVN1 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| CASP8-016 | OTTHUMT00000336855.1 | 308 | 83aa | OTTHUMP00000206553 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | H7BZM4 | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete |
| CASP8-019 | OTTHUMT00000336858.1 | 2307 | No protein | - | <p>Error in the sequence in a public database (for example UniProtKB, NCBI RefSeq). Annotation is by the <a rel="external" href="http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html">VEGA/Havana</a> project.</p>Artifact | - | - | |
| CASP8-018 | OTTHUMT00000336857.1 | 2046 | No protein | - | <p>Error in the sequence in a public database (for example UniProtKB, NCBI RefSeq). Annotation is by the <a rel="external" href="http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html">VEGA/Havana</a> project.</p>Artifact | - | - | |
| CASP8-005 | OTTHUMT00000256282.3 | 1336 | No protein | - | <p>Error in the sequence in a public database (for example UniProtKB, NCBI RefSeq). Annotation is by the <a rel="external" href="http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html">VEGA/Havana</a> project.</p>Artifact | - | - | |
| CASP8-001 | OTTHUMT00000256279.3 | 777 | 58aa | OTTHUMP00000163718 | Transcript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins. Nonsense mediated decay | - | Q14790 | |
| CASP8-008 | OTTHUMT00000257908.1 | 2911 | No protein | - | <p>Transcripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.</p>Processed transcript | - | - | |
| CASP8-011 | OTTHUMT00000257911.1 | 230 | No protein | - | <p>Transcripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.</p>Processed transcript | - | - | |
| CASP8-007 | OTTHUMT00000256283.1 | 1723 | No protein | - | <p>Alternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.</p>Retained intron | - | - | |
| CASP8-015 | OTTHUMT00000336854.1 | 969 | No protein | - | <p>Alternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.</p>Retained intron | - | - |
